Package: simplePHENOTYPES 1.3.0

Samuel Fernandes

simplePHENOTYPES: Simulation of Pleiotropic, Linked and Epistatic Phenotypes

The number of studies involving correlated traits and the availability of tools to handle this type of data has increased considerably in the last decade. With such a demand, we need tools for testing hypotheses related to single and multi-trait (correlated) phenotypes based on many genetic settings. Thus, we implemented various options for simulation of pleiotropy and Linkage Disequilibrium under additive, dominance and epistatic models. The simulation currently takes a marker data set as an input and then uses it for simulating multiple traits as described in Fernandes and Lipka (2020) <doi:10.1186/s12859-020-03804-y>.

Authors:Samuel Fernandes [aut, cre], Alexander Lipka [aut]

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simplePHENOTYPES.pdf |simplePHENOTYPES.html✨
simplePHENOTYPES/json (API)
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Peer review:

Bug tracker:https://github.com/samuelbfernandes/simplephenotypes/issues

On CRAN:

pleiotropysimulation

1 exports 11 stars 1.76 score 4 dependencies 1 mentions 15 scripts 271 downloads

Last updated 3 years agofrom:c7416412f0. Checks:OK: 3 NOTE: 4. Indexed: yes.

Exports:create_phenotypes

Dependencies:data.tablegdsfmtmvtnormSNPRelate